Tandem Labs' discovery team specializes in high-throughput analysis of non-GLP samples. Such projects include:
and other custom-screening procedures to be determined in consultation with the client and our Tandem Labs' project manager.
Non-GLP PK/PD Discovery Bioanalysis Assay Categories
The following assay categories allow our scientists to provide clients with quality data satisfying experimental objectives in the shortest time with minimal transactional overhead.
Research Grade Assay Level 1 (RGA 1)
Applicable to the early stage screening of many compounds where the objective is to provide a coarse filter of compound PK/PD, e.g., the rank ordering of compounds.
Research Grade Assay Level 2 (RGA 2)
Applicable to the later stages of screening where the objective is to provide data that supports the decision to require information of finer granularity and/or improved confidence, e.g., candidate evaluation among limited compounds, formulation assessments, etc.
Research Grade Assay Level 3 (Good Bioanalytical Practice, RGA 3)
Applicable to the latest stages of compound assessment or to bridging studies needed to support non-safety related, IND submission, e.g., definitive PK/PD studies defining dose levels in GLP nonclinical safety studies. The experimental objectives at this level require assay performance at industry standards but do not require GLP assay validation and application.