バリデートされた分析方法のリスト

バリデートされた測定法のリスト

当社は、数百に及ぶ特許化合物に対する測定法の開発及びバリデーションを行うことで、多くの製薬会社とパートナーシップを築いてまいりました。現在当社では、一連のバリデートされた測定法を構築しておりますので、御社の要望に沿った測定法のリクエストをお知らせください。

現在有効なバリデートされた非特許化合物の測定法は以下の通りです：:

List of Validated Assays
ALL A-F G-L M-R S-Z  
COMPOUND MATRIX CALIBRATION RANGE Anti-Coag LTMS TEMP
Maraviroc Human Plasma 1.00 - 1,000 ng/mL K2EDTA 180 -20
Mefenamic acid Human Plasma 50.0 - 5,000 ng/mL K3EDTA 119 -70
Memantine Human Plasma 0.100 - 100 ng/mL K3EDTA 429 -20
Mesalamine Human Plasma 2.00 to 1000 ng/mL
Metformin Human Plasma 5.00 - 5,000 ng/mL K3EDTA 56 days -70
R,S-Methadone Human Plasma 5.00 - 1,000 ng/mL K3EDTA 240 -20
Methotrexate / 7-Hydroxymethotrexate Human Plasma 1.00 - 500 ng/mL NaEDTA 527 -20
Methotrexate / 7-Hydroxymethotrexate Human Plasma 1.00 - 500 ng/mL K2EDTA 59 -20
Methotrexate / 7-Hydroxymethotrexate Human Plasma 1.00 - 500 ng/mL K2EDTA 50 -70
Methotrexate / 7-Hydroxymethotrexate Human Urine 1,000 - 50,000 ng/mL
50.0 - 2,500 ng/mL 		None 89 -20
1-Methyluric acid Human Urine 2,500 - 20,000 ng/mL None 131 -20
1-Methyluric acid Human Urine 2,500 - 20,000 ng/mL None 131 -70
1-Methylxanthine / 1,7-Dimethyluric acid Human Urine 500 - 20,000 ng/mL None 21 -20
1-Methylxanthine / 1,7-Dimethyluric acid Human Urine 500 - 50,000 ng/mL None 21 -20
Metoprolol Human Plasma 0.500 - 250 ng/mL Heparin/EDTA 121 -20,-70
Midazolam / 1-Hydroxymidazolam Human Plasma 0.100 - 10.0 ng/mL K2EDTA 1093 -20
Midazolam / 1-Hydroxymidazolam /
4-Hydroxymidazolam		 Human Plasma 0.100 - 50.0 ng/mL K2EDTA 117 -20
Moexipril / Hydrochlorothiazide Human Plasma 1.00 - 200 ng/mL K2EDTA 36 -70
Morphine / Morphine-6-glucuronide Human Plasma 0.500 - 100 ng/mL
2.5 - 500 ng/ml		 K2EDTA 462 -20
Morphine / Morphine-3-glucuronide / Morphine-6-glucuronide Human Plasma 0.500 - 50.0 ng/mL
10.0 - 1,000 ng/mL
1.00 - 100 ng/mL
Moxifloxacin Human Plasma 25.00 - 5,000 ng/mL K2EDTA 94 -20
Moxifloxacin Human Plasma 25.00 - 5,000 ng/mL NaHep 175 -20
Moxifloxacin Human Plasma 25.00 - 5,000 ng/mL Lithium Heparin 30 days -70,-20
Naltrexone / Naltrexol Human Plasma 20.0 - 2,000 pg/mL
0.500 - 50.0 ng/mL 		K2EDTA 174 -70
Naltrexone / Naltrexol Human Plasma 4.00 - 4,000 pg/mL
0.250 - 250.0 pg/mL 		K2EDTA 35 -20
Nelfinavir Human Plasma 1.00 - 1,000 ng/mL K3EDTA 100 -20
Nicotine/Cotinine Human Plasma 1.00 - 500 ng/mL
2.00 - 1,000 ng/mL		 EDTA 184,~481 -20,-70
Nifedipine Human Plasma 1.00 - 250 ng/mL K2EDTA 277 -20
Nilotinib Human Plasma 5.00 - 2,000 ng/mL K2EDTA 102 -20
Nisoldipine Human Plasma 50.0 - 10,000 pg/mL K2EDTA 288 -20
Octreotide Human Plasma 50.0 - 20,000 pg/mL
Olanzapine Human Plasma 0.400 - 100 nM K2EDTA 234 -20
Omeprazole / 5-Hydroxyomeprazole Human Plasma 10.0 - 1,000 ng/mL K3EDTA 141 -20
Oxycodone Human Plasma 0.200 - 100 ng/mL EDTA 97 -20
Oxymorphone Human Plasma 0.0500 - 25.0 ng/mL EDTA 97 -20
Paclitaxel Human Plasma 10.0 - 2,000 ng/mL K3EDTA 433 -20
Paclitaxel Human Plasma 10.0 - 5,000 ng/mL K2EDTA 164 -20,-70
Paliperidone (9-Hydroxy Risperidone) Human Plasma 0.100 - 100 nM
Pramipexole Human Plasma 50.0 - 5,000 pg/mL K3EDTA 35 -20
Pregabalin Human Plasma 50.0 - 20,000 ng/mL K2EDTA 538 -20
Quetiapine Human Plasma 0.500 - 2,000 ng/mL K2EDTA 194,3 -20,-70
Raltegravir Human Plasma 1.00 - 1,000 ng/mL
Ramelteon Human Plasma 50.0 - 8,000 pg/mL K2EDTA 95 -20
Ranolazine Human Plasma 5.00 - 5,000 ng/mL K2EDTA Pending -20,-70
Ribavarin Human Plasma 5.00 - 5,000 ng/mL K2EDTA 191 -20,-70
Rifaximin Human Plasma 0.100 - 10.0 ng/mL K2EDTA 448 -20
Riluzole Human Plasma 5.00 - 2,000 ng/mL K3EDTA -20
Riluzole Dried Blood Spot 5.00 - 2,000 ng/mL
Risperidone / 9-Hydroxy Risperidone (Paliperidone) Human Plasma 0.400 - 100 nM K2EDTA 219 -20
Rosiglitazone Human Plasma 1.00 - 1,000 ng/mL K2EDTA